Movement Disorders (revue)

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Correlation between cardiac 123I‐MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy

Identifieur interne : 003509 ( Main/Exploration ); précédent : 003508; suivant : 003510

Correlation between cardiac 123I‐MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy

Auteurs : Phil Hyu Lee [Corée du Sud] ; Seung Hyeon Yeo [Corée du Sud] ; Hyun Joon Kim [Corée du Sud] ; Hyo Young Youm [Corée du Sud]

Source :

RBID : ISTEX:900A857BC86823FAA578064365067F172BD9F9C9

English descriptors

Abstract

We investigated an association between olfaction and cardiac 123I‐metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross‐Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD. © 2006 Movement Disorder Society

Url:
DOI: 10.1002/mds.21083


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">We investigated an association between olfaction and cardiac 123I‐metaiodobenzylguanidine (MIBG) uptake in patients with Parkinson's disease (PD) and multiple system atrophy (MSA). There was a significant positive correlation between cardiac MIBG uptake and the Cross‐Cultural Smell Identification (CCSI) score in patients with PD (r = 0.56; P = 0.003) independent of the disease duration or clinical rating of motor status. However, patients with MSA did not show a significant correlation between cardiac MIBG uptake and the CCSI score. Our findings suggest that the functional losses of the olfactory and cardiac sympathetic systems are closely coupled in PD. © 2006 Movement Disorder Society</div>
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